BSPGHAN 2021 Virtual Annual Meeting

27- 29 April 2021

ASSESSING VITAMIN E STATUS IN PARENTAL NUTRITION (PN) POPULATION IN ACCORDANCE TO ESPGHAN GUIDANCE: COMPARING SERUM VITAMIN E LEVELS TO VITAMIN E:CHOLESTEROL RATIO

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Anna Pigott
Anna Pigott
19 days ago

Interesting study. Hopefully shows that you are maintaining good nutrition for your population!

Rulla Al-Araji
Rulla Al-Araji
18 days ago

Good study of the current practice and explaining lab testing for vitamin E.

David Campbell
David Campbell
18 days ago

Thank you. I wonder if your Data suggests an even stronger relationship between those two variables, if the 8mmol/l cholesterol value were excluded i.e twice the upper limit of normal. I was not clear though what the rationale is for measuring the vitamin E:cholesterol ratio (or why ESPGHAN recommended a ratio rather than a plasma concentration alone? Do you know?

Tim Morris
Tim Morris
18 days ago
Reply to  David Campbell

In the circulation Vit E is in lipoprotein particles (LDL in the main). When serum lipids are high therefore more Vit E circulates as it locates in the lipoprotein particles. When serum lipids are low, less VIt E circulates as there are less lipoprotein particles available for the VIt E to locate to. Expressing the Vit E:cholesterol ratio therefore gives a better measure of the VIt E status as high serum lipids may mask true Vit E deficiency and low serum lipids may mean a false impression of true Vit E deficiency is given.

David Campbell
David Campbell
18 days ago
Reply to  Tim Morris

Thank you. Very helpful

Farah Barakat
Farah Barakat
17 days ago

Very clear and informative study. Important for our PN practice. Thank you