BSPGHAN 2021 Virtual Annual Meeting

27- 29 April 2021

ASSESSING VITAMIN E STATUS IN PARENTAL NUTRITION (PN) POPULATION IN ACCORDANCE TO ESPGHAN GUIDANCE: COMPARING SERUM VITAMIN E LEVELS TO VITAMIN E:CHOLESTEROL RATIO

Subscribe
Notify of
6 Comments
Oldest
Newest Most Voted
Inline Feedbacks
View all comments
Anna Pigott
Anna Pigott
5 months ago

Interesting study. Hopefully shows that you are maintaining good nutrition for your population!

Rulla Al-Araji
Rulla Al-Araji
5 months ago

Good study of the current practice and explaining lab testing for vitamin E.

David Campbell
David Campbell
5 months ago

Thank you. I wonder if your Data suggests an even stronger relationship between those two variables, if the 8mmol/l cholesterol value were excluded i.e twice the upper limit of normal. I was not clear though what the rationale is for measuring the vitamin E:cholesterol ratio (or why ESPGHAN recommended a ratio rather than a plasma concentration alone? Do you know?

Tim Morris
Tim Morris
5 months ago
Reply to  David Campbell

In the circulation Vit E is in lipoprotein particles (LDL in the main). When serum lipids are high therefore more Vit E circulates as it locates in the lipoprotein particles. When serum lipids are low, less VIt E circulates as there are less lipoprotein particles available for the VIt E to locate to. Expressing the Vit E:cholesterol ratio therefore gives a better measure of the VIt E status as high serum lipids may mask true Vit E deficiency and low serum lipids may mean a false impression of true Vit E deficiency is given.

David Campbell
David Campbell
5 months ago
Reply to  Tim Morris

Thank you. Very helpful

Farah Barakat
Farah Barakat
5 months ago

Very clear and informative study. Important for our PN practice. Thank you